Gastroenterology
Watch Time: 6 mins

Kristin Kaasen Jørgensen, ECCO-IBD 2022: Proactive Therapeutic Drug Monitoring in IBD – the NOR-DRUM B Study

Published Online: March 1st 2022

We were delighted to talk with Dr Kristin Kaasen Jørgensen (Akershus University Hospital, Nordbyhagen, Norway) around the NOR-DRUM B study, investigating proactive therapeutic drug monitoring during maintenance therapy with infliximab.

The abstract entitled ‘Proactive Therapeutic Drug Monitoring is superior to standard treatment during maintenance therapy with infliximab; results from a 52-week multicentre randomised trial of 450 patients; the NOR-DRUM B study(Presentation no. OP09) was presented at the 17th Congress of ECCO, February 16-19, 2022!

Questions

  1. What are the current limitations of biologic drugs in IBD? (0:19)
  2. What are the potential benefits and pitfalls of a proactive therapeutic drug monitoring as opposed to a reactive strategy? (1:08)
  3. What were the aims and design of the NOR-DRUM B study? (2:49)
  4. What were the study endpoints and how well were these achieved? (4:24)
  5. What will be the impact of these findings on clinical practice? (5:36)

Disclosures: Kristin Kaasen Jørgensen has received personal fees from Roche, BMS, and Norgine.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Victoria Jones.

Filmed in coverage of the ECCO-IBD virtual 2022.

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