Home > Stefan Schreiber, ECCO 2021: Filgotinib for the Treatment of Ulcerative Colitis
Inflammatory Bowel Disease

Stefan Schreiber, ECCO 2021: Filgotinib for the Treatment of Ulcerative Colitis

Published Online: August 26th 2021

TouchIMMUNOLOGY had the pleasure of talking to Professor Stefan Schreiber (University Hospital Schleswig-Holstein, Kiel, Germany) around the efficacy and safety findings from the SELECTION study and its long term extension.

The abstract ‘Safety analysis of filgotinib for Ulcerative Colitis: Results from the phase 2b/3 SELECTION study and phase 3 SELECTIONLTE long-term extension study.‘ (OP04) was presented at the 16th Congress of ECCO, July 2-3 & 8-10, 2021, Virtual.

Questions

  1. What did the SELECTION study and its long term extension (LTE) teach us about the efficacy of filgotinib for the treatment of ulcerative colitis (UC)? (0:14)
  2. What safety concerns were associated with first generation JAK inhibitors, and how does filgotinib aim to overcome these? (2:21)
  3. What were the findings of your safety analysis of the SELECTION and SELECTION LTE data? (3:17)
  4. What will be the next steps for filgotinib in UC? (6:05)

Disclosures: Stefan Schreiber reports personal fees from Abbvie, Arena, BMS, Biogen, Celltrion, Celgene, IMAB, Gilead, MSD, Mylan, Pfizer, Fresenius, Janssen, Takeda, Theravance, provention Bio, Protagonist, Galapagos and Falk.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Victoria Jones.

Filmed as a highlight of ECCO 2021 (Virtual).

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