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Rheumatoid Arthritis

Roy Fleischmann, ACR 2020 – Results of the EXTEND Study

Published Online: November 25th 2020

We caught up with Roy Fleischmann (Metroplex Clinical Research Center and University of Texas Southwestern Medical Center, TX, USA) to discuss the use of sarilumab in patients with rheumatoid arthritis (Clinical Trial Identifier: NCT01146652). The abstract ‘Long-term Safety and Efficacy of Sarilumab over 5 Years in Patients with Rheumatoid Arthritis Refractory to Tumor Necrosis Factor Inhibitors’ (ABSTRACT NUMBER: 0210) was presented at the virtual ACR Convergence 2020, 5-9 November 2020.

  1. Where does sarilumab fit into the treatment paradigm for rheumatoid arthritis (RA)? (0:18)
  2. Could you tell us a little about the EXTEND study and its 5-year findings? (0:59)
  3. What were the strengths and limitations of this study and its endpoints? (1:55)
  4. How should these findings inform future clinical practice? (3:17)
  5. Which patients are most likely to benefit from sarilumab, and in whom is it contraindicated? (4:08)

Disclosure: Roy Fleischmann has nothing to disclose in relation to this video interview.

Support: Interview and filming supported by Touch Medical Media.

Filmed in coverage of the ACR 2020 Annual Meeting (Virtual).

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