Rheumatoid Arthritis

Roy Fleischmann, ACR 2021: Efficacy and Safety of Olokizumab plus Methotrexate in a Placebo and Active Controlled Study

Published Online: November 25th 2021

Dr Roy Fleischmann (University of Texas Southwestern Medical Center, Dallas, TX, USA) discusses the results from the phase 3, head-to-head, randomized, placebo-controlled clinical trial investigating olokizumab in patients with active rheumatoid arthritis inadequately controlled with methotrexate, with a comparator arm of adalimumab.

The abstract entitled ‘Efficacy and Safety of Olokizumab in a Phase III Trial of Patients with Moderately to Severely Active Rheumatoid Arthritis Inadequately Controlled by Methotrexate – Placebo and Active Controlled Study’ was presented at the ACR Convergence, 5-9 November 2021.

Questions

  1. Could you tell us a little about the aims, design and inclusion criteria of the phase 3 study you presented? (0:17)
  2. What were the efficacy and safety findings from the trial? (1:08)
  3. Where do you see olokizumab sitting in the treatment paradigm for rheumatoid arthritis? (1:43)

Disclosures: Dr Roy Fleischman has acted as a consultant for Pfizer, AbbVie, Eli Lilly, Gilead, GSK, BMS and UCB.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Gina Furnival.

Filmed in coverage of the virtual ACR Convergence 2021.

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