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    An Introduction to Type 1 Diabetes

    The immune and endocrine system interact in complex ways, and multiple immune processes are involved in endocrine diseases. The most well-known autoimmune endocrine disease is type 1 diabetes (T1D), in which autoimmune responses result in the  selective destruction of pancreatic β-cells. Other disorders resulting from autoimmune mediated tissue destruction include Grave’s disease, Hashimoto’s thyroiditis, and Addison’s disease Immune cells have been implicated in thyroid cancer development and progression, and  have also been found in adipose tissue, where they appear to play a role in glucose metabolism in the context of obesity and type 2 diabetes (T2D).

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