David R Pearson: Enpatoran for the treatment of systemic and/or cutaneous lupus erythematosus
Touch Medical Media coverage of data presented at EADV 2022:
Enpatoran is a selective dual inhibitor of TLR7 and TLR8 currently under phase 2 investigation for the treatment of systemic lupus erythematosus (SLE) and cutaneous lupus erythematosus (CLE). touchIMMUNOLOGY were delighted to speak with Dr. David R Pearson (University of Minnesota, Minneapolis, MN, USA) around the unmet needs in the treatment of SLE and CLE and the rationale for investigating enpatoran in these indications.
The abstract ‘Enpatoran: Preclinical Evidence Supporting Glucocorticoid Dose Reduction and Phase II Study Design in Patients with SLE and/or CLE (WILLOW).‘ (Abstract number: 1230) was presented at EADV 2022, 7-10 September, 2022.
Questions
- What are the unmet needs in the treatment of systemic lupus erythematosus (SLE) and/or cutaneous lupus erythematosus (CLE)? (0:20)
- What is enpatoran and what is the rationale for its use in the treatment of SLE and/or CLE? (1:09)
Disclosures: David R Pearson discloses consulting for Biogen, Inc and receiving grant/ research support from Corbus, EMD Serono, Emerald Health, Kadmon, Pfizer, and Priovant.
Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Victoria Jones.
This content was developed by Touch Medical Media and is not affiliated with the European Academy of Dermatology & Venereology (EADV) or the congress.
