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    An Introduction to Gout

    Gout, the most common inflammatory arthritis worldwide, is characterized by intense pain and impaired quality of life. Management strategies include weight management, increasing exercise and reducing alcohol consumption to reduce uric acid levels, as well as treatment with xanthine oxidase inhibitors. Other urate-lowering strategies include the selective uric acid reabsorption inhibitors lesinurad and arhalofenate. An acute attack of gout is likely to require treatment with a nonsteroidal anti-inflammatory drug (NSAID) or colchicine. Emerging anti-inflammatory strategies involving targeted anti-interleukin (IL) therapy appear effective in reducing the pain of acute attacks as well as preventing recurrent attacks. 

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